- Primary use - Hypertension
- Diarrhea in diabetics due to autonomic neuropathy-enhances salt and water reabsorption from the intestine.
- Heroin or nicotine withdrawal;
- severe pain;
- dysmenorrhea;
- vasomotor symptoms associated with menopause;
- ethanol dependence;
- prophylaxis of migraines;
- impulse control disorder,
- attention-deficit/hyperactivity disorder (ADHD),
- clozapine-induced sialorrhea
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